TY - JOUR
AU - R. Larson
AU - Thomas Perkins
AU - D. Smith
AU - S. Chu
AB - The hydrodynamics of a single, fluorescing, DNA molecule held at one end by ‘‘optical tweezers’’ and subjected to a uniform flow are compared with Monte Carlo simulations that account for the molecule’s entropic elasticity, Brownian motion, and hydrodynamic drag. Using self-diffusion data and analytic expressions to obtain the drag in the limits of the undeformed coil and of the fully stretched thread, the predicted chain stretching and mass distribution are in quantitative agreement with measurements. The results explain the success of the nonlinear elastic ‘‘dumbbell’’ model in predicting the rheological properties of dilute polymer solutions.
BT - Physical Review E
DA - 1997-02
DO - 10.1103/physreve.55.1794
IS - 2
N2 - The hydrodynamics of a single, fluorescing, DNA molecule held at one end by ‘‘optical tweezers’’ and subjected to a uniform flow are compared with Monte Carlo simulations that account for the molecule’s entropic elasticity, Brownian motion, and hydrodynamic drag. Using self-diffusion data and analytic expressions to obtain the drag in the limits of the undeformed coil and of the fully stretched thread, the predicted chain stretching and mass distribution are in quantitative agreement with measurements. The results explain the success of the nonlinear elastic ‘‘dumbbell’’ model in predicting the rheological properties of dilute polymer solutions.
PB - American Physical Society (APS)
PY - 1997
SP - 1794
EP - 1797
T2 - Physical Review E
TI - Hydrodynamics of a DNA molecule in a flow field
UR - https://journals.aps.org/pre/pdf/10.1103/PhysRevE.55.1794
VL - 55
SN - 1063-651X, 1095-3787
ER -